diff --git a/doc/api/deprecations.md b/doc/api/deprecations.md
index f10265b9ddd98a..6d3bcf75aa688b 100644
--- a/doc/api/deprecations.md
+++ b/doc/api/deprecations.md
@@ -2142,6 +2142,9 @@ parameter.
 
 <!-- YAML
 changes:
+  - version: REPLACEME
+    pr-url: https://github.com/nodejs/node/pull/55035
+    description: End-of-Life.
   - version: v10.0.0
     pr-url: https://github.com/nodejs/node/pull/18666
     description: Runtime deprecation.
@@ -2149,7 +2152,7 @@ changes:
     description: Documentation-only deprecation.
 -->
 
-Type: Runtime
+Type: End-of-Life
 
 `process.assert()` is deprecated. Please use the [`assert`][] module instead.
 
diff --git a/lib/internal/bootstrap/node.js b/lib/internal/bootstrap/node.js
index f7a62364b6107a..678e956dbd9e3c 100644
--- a/lib/internal/bootstrap/node.js
+++ b/lib/internal/bootstrap/node.js
@@ -67,10 +67,7 @@ const {
 } = primordials;
 const config = internalBinding('config');
 const internalTimers = require('internal/timers');
-const {
-  defineOperation,
-  deprecate,
-} = require('internal/util');
+const { defineOperation } = require('internal/util');
 const {
   validateInteger,
 } = require('internal/validators');
@@ -265,12 +262,6 @@ ObjectDefineProperty(process, 'allowedNodeEnvironmentFlags', {
   configurable: true,
 });
 
-// process.assert
-process.assert = deprecate(
-  perThreadSetup.assert,
-  'process.assert() is deprecated. Please use the `assert` module instead.',
-  'DEP0100');
-
 // TODO(joyeecheung): this property has not been well-maintained, should we
 // deprecate it in favor of a better API?
 const { isDebugBuild, hasOpenSSL, hasInspector } = config;
diff --git a/lib/internal/process/per_thread.js b/lib/internal/process/per_thread.js
index 70dcca3e8f0d96..506e7ee7ba2592 100644
--- a/lib/internal/process/per_thread.js
+++ b/lib/internal/process/per_thread.js
@@ -33,7 +33,6 @@ const {
 const {
   ErrnoException,
   codes: {
-    ERR_ASSERTION,
     ERR_INVALID_ARG_TYPE,
     ERR_INVALID_ARG_VALUE,
     ERR_OUT_OF_RANGE,
@@ -53,9 +52,6 @@ let getValidatedPath; // We need to lazy load it because of the circular depende
 
 const kInternal = Symbol('internal properties');
 
-function assert(x, msg) {
-  if (!x) throw new ERR_ASSERTION(msg || 'assertion error');
-}
 const { exitCodes: { kNoFailure } } = internalBinding('errors');
 
 const binding = internalBinding('process_methods');
@@ -428,7 +424,6 @@ const { arch, platform, version } = process;
 
 module.exports = {
   toggleTraceCategoryState,
-  assert,
   buildAllowedFlags,
   wrapProcessMethods,
   hrtime,
diff --git a/test/parallel/test-process-assert.js b/test/parallel/test-process-assert.js
deleted file mode 100644
index 2f0c3fc9430ce0..00000000000000
--- a/test/parallel/test-process-assert.js
+++ /dev/null
@@ -1,25 +0,0 @@
-'use strict';
-const common = require('../common');
-const assert = require('assert');
-
-common.expectWarning(
-  'DeprecationWarning',
-  'process.assert() is deprecated. Please use the `assert` module instead.',
-  'DEP0100'
-);
-
-assert.strictEqual(process.assert(1, 'error'), undefined);
-assert.throws(() => {
-  process.assert(undefined, 'errorMessage');
-}, {
-  code: 'ERR_ASSERTION',
-  name: 'Error',
-  message: 'errorMessage'
-});
-assert.throws(() => {
-  process.assert(false);
-}, {
-  code: 'ERR_ASSERTION',
-  name: 'Error',
-  message: 'assertion error'
-});